Single vial or 10-vial kit

 MOTS-C Peptide – Research-Grade Mitochondrial Peptide

MOTS-C is a mitochondrial-derived peptide studied for its role in cellular energy regulation, metabolic signaling, and mitochondrial stress adaptation. Classified as a mitochondrial exercise-mimetic peptide, MOTS-C has gained significant attention in metabolic, aging, and endurance research models.

Royal Peptides supplies high-purity, third-party tested MOTS-C for laboratory research use only, with fast fulfillment from USA & Canada warehouses.

 What Is MOTS-C?

MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA Type-C) is a 16-amino-acid peptide encoded by mitochondrial DNA rather than nuclear DNA — a rare and unique characteristic.

In preclinical research, MOTS-C has been observed to:

• Activate AMP-activated protein kinase (AMPK)
• Influence mitochondrial stress signaling
• Support metabolic flexibility
• Act as an exercise-mimetic signal in cellular models

Unlike traditional peptides synthesized from nuclear genes, MOTS-C is part of a small class of mitochondrial-encoded peptides (MDPs), placing it at the center of advanced mitochondrial biology research.

 Mechanism of Action (Research Overview)

In laboratory studies, MOTS-C has demonstrated the ability to:

• Translocate to the nucleus under metabolic stress
• Activate AMPK pathways, which regulate energy homeostasis
• Modulate glucose and fatty acid metabolism in cell models
• Support mitochondrial adaptation signaling

Researchers often categorize MOTS-C as a metabolic signaling peptide rather than a growth or structural peptide, making it especially relevant in:

• Metabolic research
• Endurance and fatigue studies
• Mitochondrial dysfunction models
• Aging-related cellular research

 Note: These effects are observed in preclinical and in-vitro research settings only.

 MOTS-C in Scientific Research

MOTS-C is frequently referenced in studies exploring:

• Exercise mimetics
• Insulin signaling pathways
• AMPK activation
• Mitochondrial communication
• Age-associated metabolic decline

Because of its mitochondrial origin, MOTS-C is considered a next-generation research peptide, often studied alongside peptides such as SS-31, NAD⁺ precursors, and mitochondrial bioregulators.

 Available MOTS-C Formats at Royal Peptides

Royal Peptides offers research-grade MOTS-C in multiple laboratory-preferred formats:

• MOTS-C 10mg
• MOTS-C 40mg
• Bulk & multi-vial kits available upon request

Each vial is:

• Lyophilized for stability
• Independently third-party tested
• Manufactured under controlled conditions
• Shipped discreetly and securely

 Quality Assurance & Testing

Every MOTS-C batch supplied by Royal Peptides includes:

• ≥99% purity verification
• Third-party analytical testing
• Identity confirmation
• Contaminant screening

Certificates of Analysis (COAs) are available for qualified researchers upon request.

 Shipping & Fulfillment

•  USA fulfillment
•  Canada fulfillment
• Same-day or next-business-day shipping on most orders
• Secure, discreet packaging

Royal Peptides specializes in fast, reliable fulfillment for both retail researchers and wholesale partners.

 Research Use Disclaimer

MOTS-C is sold strictly for laboratory research purposes only.

Not for human consumption, clinical use, or diagnostic application.

All buyers must be qualified researchers or purchasing on behalf of a research institution.